Working at MIT offers opportunities, an environment, a culture - and benefits - that just aren't found together anywhere else. If you're curious, motivated, want to be part of a unique community, and help shape the future - then take a look at this opportunity.

POSTODOCTORAL ASSOCIATE, NEUROBIOLOGY AND FLUORESCENCE IMAGING, Biological Engineering, to lead cutting-edge neurobiology and imaging research in the laboratory of Mark Bathe. The lab has developed the multichannel confocal and super-resolution fluorescence imaging approach PRISM ( http://biorxiv.org/content/early/2017/02/25/111625 ), which is now being applied to genetic and compound screens with the Broad Institute's Stanley Center for Psychiatric Research. The approach utilizes diffusible fluorescent nucleic acids that hybridize transiently to complementary nucleic acids on antibodies and mRNAs in fixed neuronal culture samples. The lab is further developing this approach to enable large-scale screens of neuronal synapse activity, including synaptic, signaling, and cytoskeletal protein and RNA targets. It is centrally interested in understanding how genetic variation related to human diseases including schizophrenia and autism impact synapse function and how compounds may be discovered to rescue normal synaptic function. Will work closely with a highly collaborative internal team of scientists and engineers at MIT and the Broad Institute, developing and applying fluorescent imaging probes based on nucleic acids to characterize proteomic and transcriptomic neuronal composition in situ.

Job Requirements
REQUIRED: a Ph.D. in biophysics, biology, bioengineering, biochemistry, chemical engineering, or a related field; extensive experience in advanced fluorescence imaging, biochemistry, and neurobiology; experience with confocal and super-resolution microscopy, neuronal cell culture, staining of neuronal cell culture samples, image processing and analysis, and basic biochemical assays (e.g., SDS page, Western Blot, etc.). Seek a highly motivated, detail-oriented individual with strong interpersonal, communication, and scientific skills. Job #14811


In addition to applying online via the MIT website with a CV and cover letter describing how this position relates to past research experience, applicants are asked to submit this information along with a list of relevant publications and contact information for three academic references to lcbb.search@gmail.com. Please use "Neurobiology Postdoctoral Research Associate" in the subject line.


5/30/17

MIT is an equal employment opportunity employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, sex, sexual orientation, gender identity, religion, disability, age, genetic information, veteran status, ancestry, or national or ethnic origin.



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